Skip to main content

Posts

Showing posts from January, 2021

CARDIOMYOPATHY

  Cardiovascular diseases are medical conditions of the heart (as the word " cardio " imply) and the blood vessels, and they are very well relevant in today's world population. Thanks to the 20th century, a large number of cardiovascular diseases have been identified. However, now that there is better awareness of these heart conditions, the mortality rate is still at a significantly high level. One of the major or primary cardiovascular diseases is cardiomyopathy .    Cardiomyopathy, in the most simplified definition, is described as a disease of the heart muscles which leads to abnormal functioning of the heart or decrease in efficiency of the heart. This eventually lead to the inability to pump blood efficiently with the heart, or circulation of blood around the body and to the heart. There are so many complications that can result from this, and cardiomyopathy is one of them.   It has three common types namely, hypertrophic cardiomyop...

HYPERLIPIDEMIA (LIPOPROTEINEMIA)

  Maintaining a balanced diet as much as possible is essential to keeping a healthy life, and one of the complications that arises from not maintaining a balanced diet is HYPERLIPIDEMIA .    Also known as Lipoproteinemia , it is a medical condition in which the level of  lipoproteins or  lipids (cholesterol, triglycerides and fats) in the blood has risen to an extremely high abnormal state which is harmful to the body and specifically to the heart. Hyperlipidemia predisposes an individual to  atherosclerosis, a condition in which the accumulation of lipid in the blood leads to the distortion of blood and oxygen passing through the veins, then to the heart, this eventually resulting to an individual having problems with his or her heart i.e the cardiovascular diseases .   Hyperlipidemia is divided into two types namely, primary hyperlipidemia and secondary hyperlipidemia. The primary hyperlipidemia are usually caused genetic...

OSTEOMYELITIS (OM)

  The rate at which Osteomyelitis develops in humans is rather not critical. However, it is a bone infection  that can sometimes be prevented. Of course, many people out there could be infected and not be calculated statistically. Without  diagnosis , the exact statistical records will remain unknown. It's complications are severe, but they are sometimes avoidable.    Osteomyelitis , also known as bone infection is usually or mostly caused by bacterial infections  and rarely caused by fungal infections . People do have varying risk of infection, however, we aren't born with o steomyelitis .    These bacterial and fungal infections are usually caused by a wound or complications resulting from a surgery. Over 80% cases of osteomyelitis are caused by open wounds . It usually starts with an open wound that's left untreated, which could eventually lead to an infection. These bacterial or fungal infections move through the blood...

MULTIPLE SCLEROSIS (MS)

  Multiple Sclerosis (MS) has been in existence for many centuries, and to even think that so far, the cause of this disease is still unclear, shows how much of a mystery this disease is, to the medical world.   In most cases of Multiple Sclerosis or  Encephalomyelitis Disseminata , the mechanism as to what led to the disease, is the destruction of  myelin sheath  by the immune system. Diseases that result from abnormal activities of the immune system are referred to as  autoimmune diseases .         An MRI scan on the brain of an MS patient   Myelin sheath surrounds the neurons (nerve cells), myelin is a lipid-rich substance that helps the neurons carry electrical signals that are used for communication between the brain (CNS) and the body. With a damaged myelin, the communication between the brain and the body is disrupted.  Oligodendrocytes are cells that are responsible for the p...

OSTEOGENESIS IMPERFECTA

  Osteogenesis imperfecta is one of the utmost concerns faced within the medical field. It is important to know that there isn't any cure for this disease, otherwise known as the brittle bone disease . However, you can learn to stay healthy, and learn to be happy living with the disease.   It is mainly caused in an autosomal dominant  manner, and it can also be caused as a result of mutations of proteins namely; COL1A1 and COL1A2 . These proteins are encoded by genes of the same name. Both COL1A1 and COL1A2 are major components of collagens , the most abundant proteins found in Mammals.    The defective genes that result from osteogenesis imperfecta, affect the production of collagens by the human body, collagens are proteins that strengthen the bone. Without abundant collagens, the bones become weak and can easily break.   Autosomal dominant simply implies that children with OI , probably inherited the disease from one of their pare...